Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression
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چکیده
منابع مشابه
Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death.
Barbiturates are widely used as anesthetics, anticonvulsants, and neuroprotective agents. However, barbiturates may also inhibit mitochondrial respiration, and mitochondrial inhibitors are known to potentiate NMDA receptor-mediated neurotoxicity. Here we used rat cortical cultures to examine the effect of barbiturates on neuronal mitochondria and responses to NMDA receptor stimulation. The barb...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2016
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.41.255